Introduction
Strongyloidiasis is a parasitic infection caused by the nematode Strongyloides stercoralis. It primarily affects tropical and subtropical regions and can persist for decades in the body if untreated. In severe cases, it can lead to hyperinfection syndrome, which is life-threatening.
What Is Strongyloidiasis?
This infection occurs when larvae in contaminated soil penetrate the skin, enter the bloodstream, and migrate to the intestines, where they mature and reproduce. The cycle continues as newly hatched larvae are excreted in stool or reinfect the host internally (autoinfection), leading to long-term infection.
Treatment & Benefits
✅ Ivermectin: The first-line treatment, killing adult worms and larvae
✅ Albendazole: An alternative medication, though less effective
✅ Prevents complications like hyperinfection and organ failure
✅ Improves quality of life by eliminating chronic symptoms
Side Effects & Risks
- Ivermectin: Dizziness, nausea, mild fever
- Albendazole: Headache, liver enzyme elevation
- Severe cases: Hyperinfection can cause respiratory distress and septic shock
⚠️ Immunocompromised individuals (e.g., HIV/AIDS, transplant patients) are at higher risk of severe disease.
Dosing & Administration
- Ivermectin: Typically 200 mcg/kg once daily for 1–2 days, but may require extended treatment for chronic cases
- Albendazole: 400 mg twice daily for 7 days (less effective than ivermectin)
🛑 Always consult a doctor for proper diagnosis and treatment.
Conclusion
Strongyloidiasis is a serious but treatable parasitic infection. Early diagnosis and ivermectin treatment are crucial, especially for immunocompromised individuals.
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